Daisypath - Anniversary

Friday, April 15, 2011

Meet my new friend,PARATHION.

IUPAC name:
O,O-Diethyl O-(4-nitrophenyl) phosphorothioate

"Parathion-methyl" (CAS#298-00-0), also known as methyl parathion or dimethyl parathion, was also developed and is marketed for similar uses. It is a distinct compound with diminished toxicity. Some trade names of parathion-methyl include Bladan MMetaphosME605, and E601.

Degradation of parathion leads to more water soluble products.
Hydrolysis, which deactivates the molecule , occurs at the aryl ester bond resulting in diethyl thiophosphate and 4-nitrophenol.

(C2H5O)2P(S)OC6H4NO2 + H2O → HOC6H4NO2 + (C2H5O)2P(S)OH

Degradations proceeds differently under anaerobic condition:
the nitro group under PARATHION is reduced to the amine.

(C2H5O)2P(S)OC6H4NO2 + 6 H → (C2H5O)2P(S)OC6H4NH2 + 2 H2O

Parathion is a cholinesterase inhibitor. It generally disrupts the nervous system by inhibiting the acetylcholinesterase.

* Why the hell am I talking about Parathion?
Lots of Love,

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